100 10406 120 Biology (ACP) 511 130 Unit 9 - DNA and Protein Synthesis 140 2 weeks 150 10 160 170 1 180 210 07.0 Science 211 4.9.3 212 5.9.4 213 6.9.10 214 215 216 220 221 222 223 224 225 226 230 231 232 233 234 235 236 240 241 242 243 244 245 246 250 251 252 253 254 255 256 300 What is the mechanism of DNA replication and how does it relate to its structure? 300 What is the mechanism of transcription? 300 What is the mechanism of translation? 300 How is it that genetic disorders are a consequence of protein synthesis aberrations? 300 How has the collaboration of multiple scientific teams resulted in the development of science theory such as DNA structure and function? 400 1. General structure of DNA and RNA 400 2. DNA replication (mechanics and evolutionary significance) 400 3. Transcription: Process (initiation, elongation, termination and associated enzymes), RNA types and functions, splicing of introns and exons 400 4. Translation: process (initiation, elongation, termination and associated enzymes), requirements, resulting protein 400 5. Protein Structure: primary, secondary, tertiary, quaternary 400 6. DNA --> RNA --> Protein --> Trait 400 7. Control of Gene expression as applies to prokaryotic systems 400 500 Students in Biology will develop the ability to: 500 1. Differentiate between DNA and RNA 500 2. Relate DNA structure to DNA replication 500 3. Relate the DNA nucleotide sequence to the amino acid sequence of the protein product (codon) 500 4. Describe and discuss Transcription and Translation 500 5. Laboratory activity - i.e., DNA extraction 500 600 1. DNA extraction 700 Objective/Subjective testing (40:60 percent) 700 Laboratory experiences - i.e. DNA extraction 700 Cooperative Activities 700 Class Discussions 800 1. DNA Technology: Karyotyping, PCR, Restriction Enzymes, Gel Electrophoresis, Recombination, Transgenetic organisms 800 2. Ethical, Legal, and Social Implications of genetic technologies 800