CURRICULUM MAP: 10406.map

Biology (ACP) 511
Unit 9 - DNA and Protein Synthesis

TIME FRAME: 2 weeks
GRADE: 10
CONTACT:

         MAP LEVEL: 1
07.0 SCIENCE

07.0.4.9.3 -- Students will explain that the structure and function of cells depends on proteins, which are made of specific sequences of amino acids coded by the DNA, that are unique to each individual

07.0.5.9.4 -- Students will explain how evolutionary relationships among organisms can be inferred from DNA and protein sequences

07.0.6.9.10 -- Students will understand that modern molecular biology allows scientists to analyze, isolate and alter genes, and this ability helps scientists in the analysis and treatment of certain diseases.



What is the mechanism of DNA replication and how does it relate to its structure?
What is the mechanism of transcription?
What is the mechanism of translation?
How is it that genetic disorders are a consequence of protein synthesis aberrations?
How has the collaboration of multiple scientific teams resulted in the development of science theory such as DNA structure and function?



1. General structure of DNA and RNA
2. DNA replication (mechanics and evolutionary significance)
3. Transcription: Process (initiation, elongation, termination and associated enzymes), RNA types and functions, splicing of introns and exons
4. Translation: process (initiation, elongation, termination and associated enzymes), requirements, resulting protein
5. Protein Structure: primary, secondary, tertiary, quaternary
6. DNA --> RNA --> Protein --> Trait
7. Control of Gene expression as applies to prokaryotic systems




Students in Biology will develop the ability to:
1. Differentiate between DNA and RNA
2. Relate DNA structure to DNA replication
3. Relate the DNA nucleotide sequence to the amino acid sequence of the protein product (codon)
4. Describe and discuss Transcription and Translation
5. Laboratory activity - i.e., DNA extraction




1. DNA extraction



Objective/Subjective testing (40:60 percent)
Laboratory experiences - i.e. DNA extraction
Cooperative Activities
Class Discussions



1. DNA Technology: Karyotyping, PCR, Restriction Enzymes, Gel Electrophoresis, Recombination, Transgenetic organisms
2. Ethical, Legal, and Social Implications of genetic technologies