100 10418 120 Biology (GEN) 513 130 Unit 7 Gen- DNA and Protein Synthesis 140 2 weeks 150 10 160 170 1 180 210 07.0 Science 211 4.9.3 212 5.9.4 213 6.9.10 214 215 216 220 08.4 Social Studies - Economics 221 1.9.5 222 3.9.2 223 224 225 226 230 09.0 Technology Education 231 2.9.1 232 2.9.2 233 234 235 236 240 241 242 243 244 245 246 250 251 252 253 254 255 256 300 What is the mechanism of DNA replication and how does it relate to its structure? 300 What is the mechanism of transcription? 300 What is the mechanism of translation? 300 How is it that genetic disorders are a consequence of protein synthesis aberations? 400 1. General structure of DNA and RNA 400 2. DNA replication (mechanics and evolutionary significance) 400 3. Transcription: process, RNA types and functions 400 4. Translation: process, requirements, resulting protein 400 5. Protein Structure: primary, secondary, tertiary, quaternary 400 6. DNA Technology: Karyotyping, PCR, RFLP, Restriction Enzymes, Gel Electrophoresis, Recombination, Transgenetic organisms 400 7. Ethical, Legal, and Social Implications of genetic technologies 400 500 Students in Biology will develop the ability to: 500 1. Differentiate between DNA and RNA, 500 2. Relate DNA structure to DNA replication, 500 3. Relate the DNA nucleotide sequence to the amino acid sequence of the protein product (codon), 500 4. Describe and discuss Transcription and Translation, 500 5. Laboratory activity - i.e., DNA extraction, 500 6. Discussion/debate regarding the ethical, legal, and social implications of genetic engineering technology. 600 1. DNA extraction 700 Objective/Subjective testing (40:60 percent) 700 Laboratory experiences - i.e. DNA extraction 700 Cooperative Activities 700 Class Discussions