CURRICULUM MAP: 10435.map
Biotechnology (ACP) 555/554
Genetic Disorders and Screening
TIME FRAME:
GRADE: 11-12
CONTACT:
MAP LEVEL:
07.0 SCIENCE
07.0.4.9.3
-- Students will explain that the structure and function of cells depends on proteins, which are made of specific sequences of amino acids coded by the DNA, that are unique to each individual
07.0.6.9.2
-- Students will compare and contrast Mendel's laws (segregation and independent assortment) or heredity
07.0.6.9.9
-- Students will explain how new heritable characteristics can result from new combinations of existing genes or from mutations of genes in reproductive cells
How do mutations and their inheritance result in genetic disorders?
How can genetic testing be used at various stages of development be used to prevent, reduce the risk of or treat genetic disorders?
What are moral and ethic issues regarding different types of genetic testing?
One of the focuses of biotechnology is to diagnose, prevent, and treat genetic disorders. In this unit student research a genetic disorder which they present to the class. Methods of genetic screening are discussed and evaluated. Social and ethical issues related to pre-implantation genetic diagnosis (PGD), newborn screening programs, and adult genetic testing are discussed.
Students in Biotechnology will develop the ability to:
A. Explain how mutation to the genetic material in the cell is responsible for genetic disorders,
B. Relate the chromosome theory of inheritance to the expression of a genetic disorder,
C. Predict the probability that a child will inherit a genetic disorder based on the genotypes of the parents using a variety of inheritance patterns (autosomal recessive and dominant, sex linked, chromosomal and codominance),
D. Apply knowledge of biochemistry concepts to the expression of a variety of genetic disorders,
E. Distinguish between life-threatening disorders, life altering disorders, and genetic difference,
F. Outline and explain approaches to preventing and treating genetic disorders and discuss what limits the ability to apply each approach,
G. Outline the process of Preimplentation Genetic Diagnosis (PGD) and evaluate its application using a variety of case studies and ethical and insurance guidelines,
H. Discuss the benefits of newborn genetic screen and evaluate the cost effectiveness of such a process in a variety of case studies,
I. Discuss the benefits and risks of genetic screening for disorders without effective treatment using Huntington Disease as a case study,
J. Evaluate the concerns regarding genetic testing and privacy, insurance coverage, and job security.
GATTACA
Genetic Disorder Poster
Subjective and Objective Testing
Genetic Disorder Poster
Graded Discussions on Genetic Testing
Movie "GATTACA"