100 10438 120 Biotechnology (ACP) 555/554 130 Molecular Biology 140 150 11-12 160 170 180 210 07.0 Science 211 4.9.3 212 213 214 215 216 220 27.3 Science - Life Science (V,VI,VII) 221 6.10.28 222 223 224 225 226 230 231 232 233 234 235 236 240 241 242 243 244 245 246 250 251 252 253 254 255 256 300 How is DNA (the material of heredity) responsible for an organism's inherited traits? 300 300 How can this process be manipulated in applications of biotechnology? 300 400 This unit reviews and expands on the molecular biology concepts initially covered in sophomore biology course. Students gain a detailed understanding of the central dogma of biology (DNA - RNA -Protein -Trait). Replication, protein synthesis and regulation of gene expression are covered in detail, preparing the students to study their applications in biotechnology. 500 Students in Biotechnology will develop the abiltiy to: 500 A. Explain how DNA gives us evidence for the unity of all life as well as the diversity, 500 B. Draw the DNA molecule and label nucleotides and their components, 500 C. Given one strand of DNA, students can draw the complimentary strand, 500 D. Create and construct 3d models of DNA with kits or their own materials, 500 E. Draw or create models to clearly demonstrate how DNA replicates, 500 F. Explain how DNA replication permits genetic information to be transmitted from generation to generation, 500 G. Demonstrate and explain that DNA nucleotide sequences carry a code, and how a simple code of four "letters" conveys a great deal of information, 500 H. Label the parts of a diagram showing protein synthesis and correctly explain the events of protein synthesis in the correct order, 500 I. Demonstrate using diagram or models how mutations can occur during replication and protein synthesis and demonstrate the functional and/or structural results of mutations, 500 J. Explain how gene expression is controlled in prokaryotic and eukaryotic cells, 500 K. Describe how a DNA microarray is used to conduct a gene expression study and interpret the results of such an experiment. 500 600 Strawberry DNA Extraction 600 pGlo Bacterial Transformation 600 DNA microarray virtual lab 600 700 Subjective and Objective Testing 700 pGlo Bacterial Transformation Lab Assessment 700 820 Genetic Science Learning Center - DNA Microarray virtual labhttp://learn.genetics.utah.edu/units/biotech/microarray/ 820 BioRad pGlo Bacterial Transformation Lab Teacher's Guide 820 820 Videos 820 "DNA- The Secret of Life" 820 "Secret of the Sequence - Green Florescent Protein" 820